Briefing

From geoengineering to anti-methane cow vaccines and green aviation fuel, meet the former nuclear physicist deciding which climate change technologies hold the most promise

A brain-computer interface has enabled a man with paralysis to have real-time conversations, without the usual delay in speech

Implants that monitor the neural activity of frog embryos as they grow into tadpoles and then adults could offer a window into the developing brain

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09112-w

A several-fold reduction in temperature is accomplished using a neutral-atom Hubbard quantum simulator by transforming a low-entropy product state into strongly correlated states of interest via dynamic control of the model parameters.

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09162-0

Lipoprotein uptake dependent on sulfated glycosaminoglycans linked to cell-surface proteoglycans is a key determinant of ferroptosis sensitivity in cancer.

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09105-9

Strong lasing effects similar to those in the optical regime can occur at 1.5–2.1 Å wavelengths during high-intensity XFEL-driven Kα1 lasing of copper and manganese.

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01782-w

Using pulses of an ultrabright X-ray free-electron laser, the structure of liquid carbon was determined at pressures exceeding one million atmospheres and temperatures of around 7,000 kelvin. This approach revealed a complex fluid with a water-like structure and an average of four neighbouring atoms around each central carbon atom.

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01583-1

A key component of the TCA cycle, a series of reactions that occurs in energy-generating organelles called mitochondria, can dictate the fate of intestinal stem cells.

Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01779-5

Experiments in mice reveal an early postnatal window of opportunity for the effective transfer of genes to blood-cell-producing haematopoietic stem cells by injecting mice with gene-carrying lentiviral vectors. This approach showed therapeutic benefit in three mouse models of severe diseases, and could expand the applicability of haematopoietic stem-cell gene therapy in the clinic.

Nature, Published online: 11 June 2025; doi:10.1038/s41586-025-09079-8

Ark+, a fully open artificial intelligence foundation model, demonstrates exceptional capabilities in diagnosing common, rare and novel thoracic diseases.